micro computed tomography microct scanning  (Bruker Corporation)

Journal: Bioactive Materials

Article Title: 3D printed scaffolds regulated by neural-bone metabolic coupling promote bone unit regeneration

doi: 10.1016/j.bioactmat.2025.10.031

Figure Lengend Snippet: In vivo experimental validation of GMN-GSE. (A) MicroCT maps of cranial defects in rat at 6 weeks and 12 weeks. (B–E) Quantitative analysis of BS, BV/TV, Tb.N, Tb.Sp at 6 weeks and 12 weeks.

Article Snippet: A SkyScan 1276 system (Bruker) was used for micro-computed tomography (MicroCT) scanning at an isotropic resolution of 18 μm.

Techniques: In Vivo, Biomarker Discovery

Journal: Cellular and Molecular Life Sciences: CMLS

Article Title: ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming

doi: 10.1007/s00018-025-06077-x

Figure Lengend Snippet: The attenuation of diabetes-induced osteoporosis through ANGPTL8 knockout. ( A ) Schematic representation of the diabetic osteoporosis model construction. ( B ) FBG levels in mice at the onset (0 weeks) and conclusion (20 weeks) of the experiment. ( C ) Body weight measurements of mice at the onset (0 weeks) and conclusion (20 weeks) of the experiment. ( D ) ELISA analysis for quantifying ANGPTL8 levels in mouse plasma. ( E ) Micro-CT imaging of mouse femurs. ( F - J ) Analysis of Micro-CT data for bone mineral density (BMD), bone volume fraction (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) in mouse femurs. Data are presented as mean ± SD; ( N = 5). ns: not significant, * p < 0.05, ** p < 0.01, *** p < 0.001

Article Snippet: The trabecular bone microarchitecture in the right femur of mice was assessed using Micro-computed tomography (Micro-CT) scanning (Quantum GX2; Perkin Elmer).

Techniques: Knock-Out, Enzyme-linked Immunosorbent Assay, Clinical Proteomics, Micro-CT, Imaging

Journal: Journal of Biomedical Optics

Article Title: Evaluation of analytical models to estimate depth of fluorescence objects in biological media

doi: 10.1117/1.JBO.31.2.026003

Figure Lengend Snippet: Experimental phantom composition. (a) Phantoms’ background absorption and reduced scattering coefficients. (b) Set of phantom molds with capillary tubes at different depths. (c) Capillary tube depth confirmation using micro-computed tomography.

Article Snippet: Once solidified, the phantoms immediately underwent fluorescence imaging followed by confirmation of fluorescent inclusion (i.e., capillary tube) depth by micro-computed tomography scanning ( 80 μ m resolution, Quantum GX3, Revvity, Waltham, Massachusetts, United States); shows an example of depth confirmation for a capillary tube of 7 mm nominal depth.

Techniques: Micro-CT

Journal: Royal Society Open Science

Article Title: Feeding without teeth: the material properties of rhamphothecae from two species of durophagous sea turtles

doi: 10.1098/rsos.221424

Figure Lengend Snippet: Rhamphotheca microCT scan segmentation (ROI selection for calculating BMD). Bruker Dataviewer software was used to view transverse (( a , e ); green), coronal (( c , g ); red) and sagittal (( d , h ); blue) CT data slices of both upper and lower rhamphothecae. ROIs were selected and BMD calculated from sagittally oriented data slices (( b , f ); blue) using Bruker CTAn software.

Article Snippet: Micro computed tomography (microCT) scans were conducted using a Bruker Skyscan 1173 (Billerica, MA, USA) at the following ranges of resolutions, voltages and amperages, respectively: 50–68 μm, 36–45 kV and 98–200 μA.

Techniques: Selection, Software